NEUROSCIENCES AND NEUROANAESTHESIA Ketamine increases the frequency of electroencephalographic bicoherence peak on the a spindle area induced with propofol

نویسندگان

  • K. Hayashi
  • N. Tsuda
  • T. Sawa
  • S. Hagihira
چکیده

Background. The reticular and thalamocortical system is known to play a prominent role in spindle wave activity, and the spindle wave is related to the sedative effects of anaesthetics. Recently, bispectral analysis of the EEG has been developed as a better method to indicate nonlinear regulation including the thalamocortical system linking to the cortical area. In the present study, in order to explore the interference of ketamine with the nonlinear regulation of the sub-cortical system, we examined the effect of ketamine on spindle a waves through the bispectral analysis.

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تاریخ انتشار 2007